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Historical Contingency Causes Divergence in Adaptive Expression of the lac Operon

Populations of Escherichia coli selected in constant and fluctuating environments containing lactose often adapt by substituting mutations in the lacI repressor that cause constitutive expression of the lac operon. These mutations occur at a high rate and provide a significant benefit. Despite this,...

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Detalles Bibliográficos
Autores principales: Karkare, Kedar, Lai, Huei-Yi, Azevedo, Ricardo B.R., Cooper, Tim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233506/
https://www.ncbi.nlm.nih.gov/pubmed/33744956
http://dx.doi.org/10.1093/molbev/msab077

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