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Historical Contingency Causes Divergence in Adaptive Expression of the lac Operon
Populations of Escherichia coli selected in constant and fluctuating environments containing lactose often adapt by substituting mutations in the lacI repressor that cause constitutive expression of the lac operon. These mutations occur at a high rate and provide a significant benefit. Despite this,...
Autores principales: | Karkare, Kedar, Lai, Huei-Yi, Azevedo, Ricardo B.R., Cooper, Tim F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233506/ https://www.ncbi.nlm.nih.gov/pubmed/33744956 http://dx.doi.org/10.1093/molbev/msab077 |
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