Cargando…

Flavonoid scutellarin positively regulates root length through NUTCRACKER

Exploring approaches to regulate meristem is of special importance and broad interest. In this study, we found that the flavonoid scutellarin, which has a 6-hydroxyl and a 7-glucoside, increased root length through the transcription factor NUTCRACKER (NUC). This root lengthening disappeared in NUC-k...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Xing, Li, Weiqi, Zhang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kunming Institute of Botany, Chinese Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233521/
https://www.ncbi.nlm.nih.gov/pubmed/34195510
http://dx.doi.org/10.1016/j.pld.2020.08.001
_version_ 1783713870877032448
author Huang, Xing
Li, Weiqi
Zhang, Xudong
author_facet Huang, Xing
Li, Weiqi
Zhang, Xudong
author_sort Huang, Xing
collection PubMed
description Exploring approaches to regulate meristem is of special importance and broad interest. In this study, we found that the flavonoid scutellarin, which has a 6-hydroxyl and a 7-glucoside, increased root length through the transcription factor NUTCRACKER (NUC). This root lengthening disappeared in NUC-knockout and reappeared in NUC-rescue plants. Scutellarin induced NUC expression and promoted the division of cortex/endodermal initials. In contrast, naringenin, which has same chemical backbone but without 6-hydroxyl and with 7-hydroxyl group, showed the opposite or no effects. Our results demonstrate that scutellarin promotes root length through NUC-mediated regulatory pathways and reveal that flavonoids with and without the 6-hydroxyl and 7-glucoside have positive and negative effects on meristem size, respectively.
format Online
Article
Text
id pubmed-8233521
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Kunming Institute of Botany, Chinese Academy of Sciences
record_format MEDLINE/PubMed
spelling pubmed-82335212021-06-29 Flavonoid scutellarin positively regulates root length through NUTCRACKER Huang, Xing Li, Weiqi Zhang, Xudong Plant Divers Research Paper Exploring approaches to regulate meristem is of special importance and broad interest. In this study, we found that the flavonoid scutellarin, which has a 6-hydroxyl and a 7-glucoside, increased root length through the transcription factor NUTCRACKER (NUC). This root lengthening disappeared in NUC-knockout and reappeared in NUC-rescue plants. Scutellarin induced NUC expression and promoted the division of cortex/endodermal initials. In contrast, naringenin, which has same chemical backbone but without 6-hydroxyl and with 7-hydroxyl group, showed the opposite or no effects. Our results demonstrate that scutellarin promotes root length through NUC-mediated regulatory pathways and reveal that flavonoids with and without the 6-hydroxyl and 7-glucoside have positive and negative effects on meristem size, respectively. Kunming Institute of Botany, Chinese Academy of Sciences 2020-08-17 /pmc/articles/PMC8233521/ /pubmed/34195510 http://dx.doi.org/10.1016/j.pld.2020.08.001 Text en © 2020 Kunming Institute of Botany, Chinese Academy of Sciences. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Paper
Huang, Xing
Li, Weiqi
Zhang, Xudong
Flavonoid scutellarin positively regulates root length through NUTCRACKER
title Flavonoid scutellarin positively regulates root length through NUTCRACKER
title_full Flavonoid scutellarin positively regulates root length through NUTCRACKER
title_fullStr Flavonoid scutellarin positively regulates root length through NUTCRACKER
title_full_unstemmed Flavonoid scutellarin positively regulates root length through NUTCRACKER
title_short Flavonoid scutellarin positively regulates root length through NUTCRACKER
title_sort flavonoid scutellarin positively regulates root length through nutcracker
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233521/
https://www.ncbi.nlm.nih.gov/pubmed/34195510
http://dx.doi.org/10.1016/j.pld.2020.08.001
work_keys_str_mv AT huangxing flavonoidscutellarinpositivelyregulatesrootlengththroughnutcracker
AT liweiqi flavonoidscutellarinpositivelyregulatesrootlengththroughnutcracker
AT zhangxudong flavonoidscutellarinpositivelyregulatesrootlengththroughnutcracker