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CRISPR/Cas9-based generation of a recombinant double-reporter pseudorabies virus and its characterization in vitro and in vivo

Pseudorabies, caused by pseudorabies virus (PRV) variants, has broken out among commercial PRV vaccine-immunized swine herds and resulted in major economic losses to the pig industry in China since late 2011. However, the mechanism of virulence enhancement of variant PRV is currently unclear. Here,...

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Detalles Bibliográficos
Autores principales:	Fu, Peng-Fei, Cheng, Xuan, Su, Bing-Qian, Duan, Li-Fang, Wang, Cong-Rong, Niu, Xin-Rui, Wang, Jiang, Yang, Guo-Yu, Chu, Bei-Bei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233574/ https://www.ncbi.nlm.nih.gov/pubmed/34174954 http://dx.doi.org/10.1186/s13567-021-00964-4

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