A muscle fatigue-like contractile decline was recapitulated using skeletal myotubes from Duchenne muscular dystrophy patient-derived iPSCs

Duchenne muscular dystrophy (DMD) is a muscle degenerating disease caused by dystrophin deficiency, for which therapeutic options are limited. To facilitate drug development, it is desirable to develop in vitro disease models that enable the evaluation of DMD declines in contractile performance. Her...

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Detalles Bibliográficos
Autores principales: Uchimura, Tomoya, Asano, Toshifumi, Nakata, Takao, Hotta, Akitsu, Sakurai, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233665/
https://www.ncbi.nlm.nih.gov/pubmed/34195678
http://dx.doi.org/10.1016/j.xcrm.2021.100298

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