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Miniaturization and Automation of a Human In Vitro Blood–Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery
Central nervous system (CNS) diseases are one of the top causes of death worldwide. As there is a difficulty of drug penetration into the brain due to the blood–brain barrier (BBB), many CNS drugs treatments fail in clinical trials. Hence, there is a need to develop effective CNS drugs following str...
Autores principales: | Moya, Elisa L. J., Vandenhaute, Elodie, Rizzi, Eleonora, Boucau, Marie-Christine, Hachani, Johan, Maubon, Nathalie, Gosselet, Fabien, Dehouck, Marie-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233835/ https://www.ncbi.nlm.nih.gov/pubmed/34208550 http://dx.doi.org/10.3390/pharmaceutics13060892 |
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