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The Effects of N-Acetylcysteine on the Rat Mesocorticolimbic Pathway: Role of mGluR5 Receptors and Interaction with Ethanol

N-acetylcysteine (NAC) is a prodrug that is marketed as a mucolytic agent and used for the treatment of acetaminophen overdose. Over the last few decades, evidence has been gathered that suggests the potential use of NAC as a new pharmacotherapy for alcohol use disorder (AUD), although its mechanism...

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Detalles Bibliográficos
Autores principales: Fernández-Rodríguez, Sandra, Esposito-Zapero, Claudia, Zornoza, Teodoro, Polache, Ana, Granero, Luis, Cano-Cebrián, María José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233914/
https://www.ncbi.nlm.nih.gov/pubmed/34203104
http://dx.doi.org/10.3390/ph14060593

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