Cargando…
Evaluation of Benzguinols as Next-Generation Antibiotics for the Treatment of Multidrug-Resistant Bacterial Infections
Our recent focus on the “lost antibiotic” unguinol and related nidulin-family fungal natural products identified two semisynthetic derivatives, benzguinols A and B, with unexpected in vitro activity against Staphylococcus aureus isolates either susceptible or resistant to methicillin. Here, we show...
Autores principales: | Nguyen, Hang Thi, Morshed, Mahmud T., Vuong, Daniel, Crombie, Andrew, Lacey, Ernest, Garg, Sanjay, Pi, Hongfei, Woolford, Lucy, Venter, Henrietta, Page, Stephen W., Piggott, Andrew M., Trott, Darren J., Ogunniyi, Abiodun D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233939/ https://www.ncbi.nlm.nih.gov/pubmed/34208698 http://dx.doi.org/10.3390/antibiotics10060727 |
Ejemplares similares
-
Repurposing of the Fasciolicide Triclabendazole to Treat Infections Caused by Staphylococcus spp. and Vancomycin-Resistant Enterococci
por: Pi, Hongfei, et al.
Publicado: (2021) -
Impact of a Novel Anticoccidial Analogue on Systemic Staphylococcus aureus Infection in a Bioluminescent Mouse Model
por: Nguyen, Hang Thi, et al.
Publicado: (2022) -
In vitro Activity of Robenidine Analog NCL195 in Combination With Outer Membrane Permeabilizers Against Gram-Negative Bacterial Pathogens and Impact on Systemic Gram-Positive Bacterial Infection in Mice
por: Pi, Hongfei, et al.
Publicado: (2020) -
In Vitro Activity of Robenidine Analogues NCL259 and NCL265 against Gram-Negative Pathogens
por: Pi, Hongfei, et al.
Publicado: (2022) -
In vitro Antimicrobial Activity of Robenidine, Ethylenediaminetetraacetic Acid and Polymyxin B Nonapeptide Against Important Human and Veterinary Pathogens
por: Khazandi, Manouchehr, et al.
Publicado: (2019)