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COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye

Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread t...

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Detalles Bibliográficos
Autores principales: Bhogal, Pervinder, Makalanda, Levansri, Hassan, Ameer E., Fiorella, Dave, Andersson, Tommy, Ahmad, Muhammad, Bäzner, Hansjörg, Jaffer, Ounali, Henkes, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233948/
https://www.ncbi.nlm.nih.gov/pubmed/34208470
http://dx.doi.org/10.3390/jcm10122646
Descripción
Sumario:Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread thrombosis and in particular a microthrombosis. The mechanisms involved in the microthrombosis are not confined to infection and there is evidence that patients with aneurysmal sub-arachnoid haemorrhage (SAH) also suffer from an endotheliopathy and microthrombosis. In this article we attempt to shed light on similarities in the underlying processes involved in both diseases and suggest potential treatment options.