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COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye
Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233948/ https://www.ncbi.nlm.nih.gov/pubmed/34208470 http://dx.doi.org/10.3390/jcm10122646 |
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author | Bhogal, Pervinder Makalanda, Levansri Hassan, Ameer E. Fiorella, Dave Andersson, Tommy Ahmad, Muhammad Bäzner, Hansjörg Jaffer, Ounali Henkes, Hans |
author_facet | Bhogal, Pervinder Makalanda, Levansri Hassan, Ameer E. Fiorella, Dave Andersson, Tommy Ahmad, Muhammad Bäzner, Hansjörg Jaffer, Ounali Henkes, Hans |
author_sort | Bhogal, Pervinder |
collection | PubMed |
description | Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread thrombosis and in particular a microthrombosis. The mechanisms involved in the microthrombosis are not confined to infection and there is evidence that patients with aneurysmal sub-arachnoid haemorrhage (SAH) also suffer from an endotheliopathy and microthrombosis. In this article we attempt to shed light on similarities in the underlying processes involved in both diseases and suggest potential treatment options. |
format | Online Article Text |
id | pubmed-8233948 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82339482021-06-27 COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye Bhogal, Pervinder Makalanda, Levansri Hassan, Ameer E. Fiorella, Dave Andersson, Tommy Ahmad, Muhammad Bäzner, Hansjörg Jaffer, Ounali Henkes, Hans J Clin Med Review Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread thrombosis and in particular a microthrombosis. The mechanisms involved in the microthrombosis are not confined to infection and there is evidence that patients with aneurysmal sub-arachnoid haemorrhage (SAH) also suffer from an endotheliopathy and microthrombosis. In this article we attempt to shed light on similarities in the underlying processes involved in both diseases and suggest potential treatment options. MDPI 2021-06-16 /pmc/articles/PMC8233948/ /pubmed/34208470 http://dx.doi.org/10.3390/jcm10122646 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bhogal, Pervinder Makalanda, Levansri Hassan, Ameer E. Fiorella, Dave Andersson, Tommy Ahmad, Muhammad Bäzner, Hansjörg Jaffer, Ounali Henkes, Hans COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye |
title | COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye |
title_full | COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye |
title_fullStr | COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye |
title_full_unstemmed | COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye |
title_short | COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye |
title_sort | covid-19 and delayed cerebral ischemia—more in common than first meets the eye |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233948/ https://www.ncbi.nlm.nih.gov/pubmed/34208470 http://dx.doi.org/10.3390/jcm10122646 |
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