Cargando…

COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye

Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread t...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhogal, Pervinder, Makalanda, Levansri, Hassan, Ameer E., Fiorella, Dave, Andersson, Tommy, Ahmad, Muhammad, Bäzner, Hansjörg, Jaffer, Ounali, Henkes, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233948/
https://www.ncbi.nlm.nih.gov/pubmed/34208470
http://dx.doi.org/10.3390/jcm10122646
_version_ 1783713968759504896
author Bhogal, Pervinder
Makalanda, Levansri
Hassan, Ameer E.
Fiorella, Dave
Andersson, Tommy
Ahmad, Muhammad
Bäzner, Hansjörg
Jaffer, Ounali
Henkes, Hans
author_facet Bhogal, Pervinder
Makalanda, Levansri
Hassan, Ameer E.
Fiorella, Dave
Andersson, Tommy
Ahmad, Muhammad
Bäzner, Hansjörg
Jaffer, Ounali
Henkes, Hans
author_sort Bhogal, Pervinder
collection PubMed
description Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread thrombosis and in particular a microthrombosis. The mechanisms involved in the microthrombosis are not confined to infection and there is evidence that patients with aneurysmal sub-arachnoid haemorrhage (SAH) also suffer from an endotheliopathy and microthrombosis. In this article we attempt to shed light on similarities in the underlying processes involved in both diseases and suggest potential treatment options.
format Online
Article
Text
id pubmed-8233948
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-82339482021-06-27 COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye Bhogal, Pervinder Makalanda, Levansri Hassan, Ameer E. Fiorella, Dave Andersson, Tommy Ahmad, Muhammad Bäzner, Hansjörg Jaffer, Ounali Henkes, Hans J Clin Med Review Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread thrombosis and in particular a microthrombosis. The mechanisms involved in the microthrombosis are not confined to infection and there is evidence that patients with aneurysmal sub-arachnoid haemorrhage (SAH) also suffer from an endotheliopathy and microthrombosis. In this article we attempt to shed light on similarities in the underlying processes involved in both diseases and suggest potential treatment options. MDPI 2021-06-16 /pmc/articles/PMC8233948/ /pubmed/34208470 http://dx.doi.org/10.3390/jcm10122646 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bhogal, Pervinder
Makalanda, Levansri
Hassan, Ameer E.
Fiorella, Dave
Andersson, Tommy
Ahmad, Muhammad
Bäzner, Hansjörg
Jaffer, Ounali
Henkes, Hans
COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye
title COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye
title_full COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye
title_fullStr COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye
title_full_unstemmed COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye
title_short COVID-19 and Delayed Cerebral Ischemia—More in Common Than First Meets the Eye
title_sort covid-19 and delayed cerebral ischemia—more in common than first meets the eye
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233948/
https://www.ncbi.nlm.nih.gov/pubmed/34208470
http://dx.doi.org/10.3390/jcm10122646
work_keys_str_mv AT bhogalpervinder covid19anddelayedcerebralischemiamoreincommonthanfirstmeetstheeye
AT makalandalevansri covid19anddelayedcerebralischemiamoreincommonthanfirstmeetstheeye
AT hassanameere covid19anddelayedcerebralischemiamoreincommonthanfirstmeetstheeye
AT fiorelladave covid19anddelayedcerebralischemiamoreincommonthanfirstmeetstheeye
AT anderssontommy covid19anddelayedcerebralischemiamoreincommonthanfirstmeetstheeye
AT ahmadmuhammad covid19anddelayedcerebralischemiamoreincommonthanfirstmeetstheeye
AT baznerhansjorg covid19anddelayedcerebralischemiamoreincommonthanfirstmeetstheeye
AT jafferounali covid19anddelayedcerebralischemiamoreincommonthanfirstmeetstheeye
AT henkeshans covid19anddelayedcerebralischemiamoreincommonthanfirstmeetstheeye