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Laser-facilitated epicutaneous immunization of mice with SARS-CoV-2 spike protein induces antibodies inhibiting spike/ACE2 binding

The skin represents an attractive target tissue for vaccination against respiratory viruses such as SARS-CoV-2. Laser-facilitated epicutaneous immunization (EPI) has been established as a novel technology to overcome the skin barrier, which combines efficient delivery via micropores with an inherent...

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Detalles Bibliográficos
Autores principales: Scheiblhofer, Sandra, Drothler, Stephan, Braun, Werner, Braun, Reinhard, Boesch, Maximilian, Weiss, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233963/
https://www.ncbi.nlm.nih.gov/pubmed/34226102
http://dx.doi.org/10.1016/j.vaccine.2021.06.068