Fructose Causes Liver Damage, Polyploidy, and Dysplasia in the Setting of Short Telomeres and p53 Loss

Studies in humans and model systems have established an important role of short telomeres in predisposing to liver fibrosis through pathways that are incompletely understood. Recent studies have shown that telomere dysfunction impairs cellular metabolism, but whether and how these metabolic alterati...

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Detalles Bibliográficos
Autores principales: Chronowski, Christopher, Akhanov, Viktor, Chan, Doug, Catic, Andre, Finegold, Milton, Sahin, Ergün
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234056/
https://www.ncbi.nlm.nih.gov/pubmed/34204343
http://dx.doi.org/10.3390/metabo11060394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234056/
https://www.ncbi.nlm.nih.gov/pubmed/34204343
http://dx.doi.org/10.3390/metabo11060394

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