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Fructose Causes Liver Damage, Polyploidy, and Dysplasia in the Setting of Short Telomeres and p53 Loss
Studies in humans and model systems have established an important role of short telomeres in predisposing to liver fibrosis through pathways that are incompletely understood. Recent studies have shown that telomere dysfunction impairs cellular metabolism, but whether and how these metabolic alterati...
Autores principales: | Chronowski, Christopher, Akhanov, Viktor, Chan, Doug, Catic, Andre, Finegold, Milton, Sahin, Ergün |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234056/ https://www.ncbi.nlm.nih.gov/pubmed/34204343 http://dx.doi.org/10.3390/metabo11060394 |
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