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Strength and Numbers: The Role of Affinity and Avidity in the ‘Quality’ of T Cell Tolerance
The ability of T cells to identify foreign antigens and mount an efficient immune response while limiting activation upon recognition of self and self-associated peptides is critical. Multiple tolerance mechanisms work in concert to prevent the generation and activation of self-reactive T cells. T c...
Autores principales: | This, Sébastien, Valbon, Stefanie F., Lebel, Marie-Ève, Melichar, Heather J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234061/ https://www.ncbi.nlm.nih.gov/pubmed/34204485 http://dx.doi.org/10.3390/cells10061530 |
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