Facile N9-Alkylation of Xanthine Derivatives and Their Use as Precursors for N-Heterocyclic Carbene Complexes

The xanthine-derivatives 1,3,7-trimethylxanthine, 1,3-dimethyl-7-benzylxanthine and 1,3-dimethyl-7-(4-chlorobenzyl)xanthine are readily ethylated at N9 using the cheap alkylating agents ethyl tosylate or diethyl sulfate. The resulting xanthinium tosylate or ethyl sulfate salts can be converted into...

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Detalles Bibliográficos
Autores principales: Mokfi, Moloud, Rust, Jörg, Lehmann, Christian W., Mohr, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234118/
https://www.ncbi.nlm.nih.gov/pubmed/34204439
http://dx.doi.org/10.3390/molecules26123705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234118/
https://www.ncbi.nlm.nih.gov/pubmed/34204439
http://dx.doi.org/10.3390/molecules26123705

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