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Phosphorylation of human phospholipase A1 DDHD1 at newly identified phosphosites affects its subcellular localization

Phospholipase A1 (PLA1) hydrolyzes the fatty acids of glycerophospholipids, which are structural components of the cellular membrane. Genetic mutations in DDHD1, an intracellular PLA1, result in hereditary spastic paraplegia (HSP) in humans. However, the regulation of DDHD1 activity has not yet been...

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Detalles Bibliográficos
Autores principales:	Matsumoto, Naoki, Nemoto-Sasaki, Yoko, Oka, Saori, Arai, Seisuke, Wada, Ikuo, Yamashita, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234217/ https://www.ncbi.nlm.nih.gov/pubmed/34089703 http://dx.doi.org/10.1016/j.jbc.2021.100851

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