Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers

The incidence of various types of cancer is increasing globally. To reduce the critical side effects of cancer chemotherapy, naturally derived compounds have been considered for cancer treatment. Gymnosperms are a group of plants found worldwide that have traditionally been used for therapeutic appl...

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Autores principales: Ghaffari, Tayyebeh, Hong, Joo-Hyun, Asnaashari, Solmaz, Farajnia, Safar, Delazar, Abbas, Hamishehkar, Hamed, Kim, Ki-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234227/
https://www.ncbi.nlm.nih.gov/pubmed/34205739
http://dx.doi.org/10.3390/ijms22126636
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author Ghaffari, Tayyebeh
Hong, Joo-Hyun
Asnaashari, Solmaz
Farajnia, Safar
Delazar, Abbas
Hamishehkar, Hamed
Kim, Ki-Hyun
author_facet Ghaffari, Tayyebeh
Hong, Joo-Hyun
Asnaashari, Solmaz
Farajnia, Safar
Delazar, Abbas
Hamishehkar, Hamed
Kim, Ki-Hyun
author_sort Ghaffari, Tayyebeh
collection PubMed
description The incidence of various types of cancer is increasing globally. To reduce the critical side effects of cancer chemotherapy, naturally derived compounds have been considered for cancer treatment. Gymnosperms are a group of plants found worldwide that have traditionally been used for therapeutic applications. Paclitaxel is a commercially available anticancer drug derived from gymnosperms. Other natural compounds with anticancer activities, such as pinostrobin and pinocembrin, are extracted from pine heartwood, and pycnogenol and enzogenol from pine bark. Gymnosperms have great potential for further study for the discovery of new anticancer compounds. This review aims to provide a rational understanding and the latest developments in potential anticancer compounds derived from gymnosperms.
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spelling pubmed-82342272021-06-27 Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers Ghaffari, Tayyebeh Hong, Joo-Hyun Asnaashari, Solmaz Farajnia, Safar Delazar, Abbas Hamishehkar, Hamed Kim, Ki-Hyun Int J Mol Sci Review The incidence of various types of cancer is increasing globally. To reduce the critical side effects of cancer chemotherapy, naturally derived compounds have been considered for cancer treatment. Gymnosperms are a group of plants found worldwide that have traditionally been used for therapeutic applications. Paclitaxel is a commercially available anticancer drug derived from gymnosperms. Other natural compounds with anticancer activities, such as pinostrobin and pinocembrin, are extracted from pine heartwood, and pycnogenol and enzogenol from pine bark. Gymnosperms have great potential for further study for the discovery of new anticancer compounds. This review aims to provide a rational understanding and the latest developments in potential anticancer compounds derived from gymnosperms. MDPI 2021-06-21 /pmc/articles/PMC8234227/ /pubmed/34205739 http://dx.doi.org/10.3390/ijms22126636 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ghaffari, Tayyebeh
Hong, Joo-Hyun
Asnaashari, Solmaz
Farajnia, Safar
Delazar, Abbas
Hamishehkar, Hamed
Kim, Ki-Hyun
Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers
title Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers
title_full Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers
title_fullStr Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers
title_full_unstemmed Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers
title_short Natural Phytochemicals Derived from Gymnosperms in the Prevention and Treatment of Cancers
title_sort natural phytochemicals derived from gymnosperms in the prevention and treatment of cancers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234227/
https://www.ncbi.nlm.nih.gov/pubmed/34205739
http://dx.doi.org/10.3390/ijms22126636
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