Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece

We analyzed the antibody responses of 564 hospital workers in Athens, Greece, after vaccination with two doses of the BNT162b2 (Comirnaty(®); BioNTech and Pfizer) mRNA COVID-19 vaccine. A greater antibody increase was observed in women, younger age groups, previously infected individuals and personn...

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Autores principales: Kontou, Elissavet, Ranellou, Kyriaki, Zoulas, Dimitrios, Bletsa, Anastasia, Rompola, Eirini, Piperaki, Evangelia-Theophano, Athanasiou, Nikolaos, Ampelakiotou, Kleio, Pratikaki, Maria, Stergiopoulou, Christina, Argyropoulou, Athina, Alevra, Androula, Megalou, Aggeliki, Tsirogianni, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234272/
https://www.ncbi.nlm.nih.gov/pubmed/34205301
http://dx.doi.org/10.3390/jpm11060576
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author Kontou, Elissavet
Ranellou, Kyriaki
Zoulas, Dimitrios
Bletsa, Anastasia
Rompola, Eirini
Piperaki, Evangelia-Theophano
Athanasiou, Nikolaos
Ampelakiotou, Kleio
Pratikaki, Maria
Stergiopoulou, Christina
Argyropoulou, Athina
Alevra, Androula
Megalou, Aggeliki
Tsirogianni, Alexandra
author_facet Kontou, Elissavet
Ranellou, Kyriaki
Zoulas, Dimitrios
Bletsa, Anastasia
Rompola, Eirini
Piperaki, Evangelia-Theophano
Athanasiou, Nikolaos
Ampelakiotou, Kleio
Pratikaki, Maria
Stergiopoulou, Christina
Argyropoulou, Athina
Alevra, Androula
Megalou, Aggeliki
Tsirogianni, Alexandra
author_sort Kontou, Elissavet
collection PubMed
description We analyzed the antibody responses of 564 hospital workers in Athens, Greece, after vaccination with two doses of the BNT162b2 (Comirnaty(®); BioNTech and Pfizer) mRNA COVID-19 vaccine. A greater antibody increase was observed in women, younger age groups, previously infected individuals and personnel working in COVID-19 clinics. Notably, individuals with a prior COVID-19 infection mounted a significantly higher antibody titer following the first dose than the rest of the population; the same was true for those working in COVID-19 clinics, even without history of previous infection.
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spelling pubmed-82342722021-06-27 Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece Kontou, Elissavet Ranellou, Kyriaki Zoulas, Dimitrios Bletsa, Anastasia Rompola, Eirini Piperaki, Evangelia-Theophano Athanasiou, Nikolaos Ampelakiotou, Kleio Pratikaki, Maria Stergiopoulou, Christina Argyropoulou, Athina Alevra, Androula Megalou, Aggeliki Tsirogianni, Alexandra J Pers Med Communication We analyzed the antibody responses of 564 hospital workers in Athens, Greece, after vaccination with two doses of the BNT162b2 (Comirnaty(®); BioNTech and Pfizer) mRNA COVID-19 vaccine. A greater antibody increase was observed in women, younger age groups, previously infected individuals and personnel working in COVID-19 clinics. Notably, individuals with a prior COVID-19 infection mounted a significantly higher antibody titer following the first dose than the rest of the population; the same was true for those working in COVID-19 clinics, even without history of previous infection. MDPI 2021-06-19 /pmc/articles/PMC8234272/ /pubmed/34205301 http://dx.doi.org/10.3390/jpm11060576 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Kontou, Elissavet
Ranellou, Kyriaki
Zoulas, Dimitrios
Bletsa, Anastasia
Rompola, Eirini
Piperaki, Evangelia-Theophano
Athanasiou, Nikolaos
Ampelakiotou, Kleio
Pratikaki, Maria
Stergiopoulou, Christina
Argyropoulou, Athina
Alevra, Androula
Megalou, Aggeliki
Tsirogianni, Alexandra
Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece
title Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece
title_full Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece
title_fullStr Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece
title_full_unstemmed Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece
title_short Antibody Response Following a Two-Dose mRNA Vaccination Regimen, in Health Care Workers of a Tertiary Hospital in Athens, Greece
title_sort antibody response following a two-dose mrna vaccination regimen, in health care workers of a tertiary hospital in athens, greece
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234272/
https://www.ncbi.nlm.nih.gov/pubmed/34205301
http://dx.doi.org/10.3390/jpm11060576
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