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Pharmacodynamics and Outcomes of a De-Escalation Strategy with Half-Dose Prasugrel or Ticagrelor in East Asians Patients with Acute Coronary Syndrome: Results from HOPE-TAILOR Trial
East Asians treated with potent P2Y12 inhibitors (prasugrel or ticagrelor) generally experience more intense platelet inhibitory responses resulting in an increased risk of major bleeding. Whether a half-dose de-escalation strategy improves the net clinical benefit in Korean patients with acute coro...
Autores principales: | Jin, Cai-De, Kim, Moo-Hyun, Song, Kai, Jin, Xuan, Lee, Kwang-Min, Park, Jong-Sung, Cho, Young-Rak, Yun, Sung-Cheol, Lee, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234416/ https://www.ncbi.nlm.nih.gov/pubmed/34207339 http://dx.doi.org/10.3390/jcm10122699 |
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