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Statistical Approach to Incorporating Experimental Variability into a Mathematical Model of the Voltage-Gated Na(+) Channel and Human Atrial Action Potential

The voltage-gated Na(+) channel Na(v)1.5 is critical for normal cardiac myocyte excitability. Mathematical models have been widely used to study Na(v)1.5 function and link to a range of cardiac arrhythmias. There is growing appreciation for the importance of incorporating physiological heterogeneity...

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Detalles Bibliográficos
Autores principales:	Gratz, Daniel, Winkle, Alexander J, Weinberg, Seth H, Hund, Thomas J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234464/ https://www.ncbi.nlm.nih.gov/pubmed/34208565 http://dx.doi.org/10.3390/cells10061516

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