Cargando…
Immune Cell Modulation of the Extracellular Matrix Contributes to the Pathogenesis of Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a five-year survival rate of only 9%. PDAC is characterized by a dense, fibrotic stroma composed of extracellular matrix (ECM) proteins. This desmoplastic stroma is a hallmark of PDAC, representing a significant physical barr...
Autores principales: | Ahmad, Ramiz S., Eubank, Timothy D., Lukomski, Slawomir, Boone, Brian A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234537/ https://www.ncbi.nlm.nih.gov/pubmed/34204306 http://dx.doi.org/10.3390/biom11060901 |
Ejemplares similares
-
Emerging applications of cancer bacteriotherapy towards treatment of pancreatic cancer
por: Henderson, Emily A., et al.
Publicado: (2023) -
Macrophage and Neutrophil Interactions in the Pancreatic Tumor Microenvironment Drive the Pathogenesis of Pancreatic Cancer
por: Pratt, Hillary G., et al.
Publicado: (2021) -
Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets
por: Llacua, L. Alberto, et al.
Publicado: (2018) -
Adaptation of the group A Streptococcus adhesin Scl1 to bind fibronectin type III repeats within wound‐associated extracellular matrix: implications for cancer therapy
por: McNitt, Dudley H., et al.
Publicado: (2019) -
Role of the Extracellular Matrix in the Pathogenesis of Hypertrophic Cardiomyopathy
por: Marian, Ali J.
Publicado: (2019)