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Development of a Macrophage-Based ADCC Assay

Fc-dependent effector functions are an important determinant of the in vivo potency of therapeutic antibodies. Effector function is determined by the combination of FcRs bound by the antibody and the cell expressing the relevant FcRs, leading to antibody-dependent cellular cytotoxicity (ADCC). A num...

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Detalles Bibliográficos
Autores principales:	Uccellini, Melissa B., Aslam, Sadaf, Liu, Sean T. H., Alam, Fahmida, García-Sastre, Adolfo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234572/ https://www.ncbi.nlm.nih.gov/pubmed/34204268 http://dx.doi.org/10.3390/vaccines9060660

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