In Vitro Effects of Selective COX and LOX Inhibitors and Their Combinations with Antineoplastic Drugs in the Mouse Melanoma Cell Line B16F10

The constitutive expression or overactivation of cyclooxygenase (COX) and lipoxygenase (LOX) enzymes results in aberrant metabolism of arachidonic acid and poor prognosis in melanoma. Our aim is to compare the in vitro effects of selective COX-1 (acetylsalicylic acid), COX-2 (meloxicam), 5-LOX (MK-8...

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Detalles Bibliográficos
Autores principales: Da-Costa-Rocha, Ines, Prieto, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234702/
https://www.ncbi.nlm.nih.gov/pubmed/34204367
http://dx.doi.org/10.3390/ijms22126498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234702/
https://www.ncbi.nlm.nih.gov/pubmed/34204367
http://dx.doi.org/10.3390/ijms22126498

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