Cargando…

The Potential Role of Sildenafil in Cancer Management through EPR Augmentation

Enhanced permeation retention (EPR) was a significant milestone discovery by Maeda et al. paving the path for the emerging field of nanomedicine to become a powerful tool in the fight against cancer. Sildenafil is a potent inhibitor of phosphodiesterase 5 (PDE-5) used for the treatment of erectile d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Haider, Mohamed, Elsherbeny, Amr, Pittalà, Valeria, Fallica, Antonino N., Alghamdi, Maha Ali, Greish, Khaled
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234771/ https://www.ncbi.nlm.nih.gov/pubmed/34205602 http://dx.doi.org/10.3390/jpm11060585

Ejemplares similares

Nanomedicine Strategies for Management of Drug Resistance in Lung Cancer
por: Haider, Mohamed, et al.
Publicado: (2022)

The Promise of Nanotechnology in Personalized Medicine
por: Alghamdi, Maha Ali, et al.
Publicado: (2022)

Curcumin I-SMA nanomicelles as promising therapeutic tool to tackle bacterial infections
por: Virzì, Nicola F., et al.
Publicado: (2023)

From Far West to East: Joining the Molecular Architecture of Imidazole-like Ligands in HO-1 Complexes
por: Floresta, Giuseppe, et al.
Publicado: (2021)

Enhanced Anticancer Activity of Nanoformulation of Dasatinib against Triple-Negative Breast Cancer
por: Bahman, Fatemah, et al.
Publicado: (2021)

In Vivo Evaluation of Anti-Nociceptive Effects of Silver Nanoparticles
por: Morsi, Shereen, et al.
Publicado: (2022)

Selective Targeting of Breast Cancer by Tafuramycin A Using SMA-Nanoassemblies
por: El-Deeb, Ibrahim M., et al.
Publicado: (2021)

Nitric oxide-releasing nanoparticles improve doxorubicin anticancer activity
por: Alimoradi, Houman, et al.
Publicado: (2018)

Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective
por: Fallica, Antonino N., et al.
Publicado: (2021)

Is Sildenafil an Effective Therapy in the Management of Persistent Pulmonary Hypertension?
por: Yaseen, Hakam, et al.
Publicado: (2012)

Novel Heme Oxygenase-1 (HO-1) Inducers Based on Dimethyl Fumarate Structure
por: Sorrenti, Valeria, et al.
Publicado: (2020)

Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells
por: Consoli, Valeria, et al.
Publicado: (2022)

Curcumin–Copper Complex Nanoparticles for the Management of Triple-Negative Breast Cancer
por: Greish, Khaled, et al.
Publicado: (2018)

Optimization and Evaluation of Poly(lactide-co-glycolide) Nanoparticles for Enhanced Cellular Uptake and Efficacy of Paclitaxel in the Treatment of Head and Neck Cancer
por: Haider, Mohamed, et al.
Publicado: (2020)

Augmentation of EPR Effect and Efficacy of Anticancer Nanomedicine by Carbon Monoxide Generating Agents
por: Fang, Jun, et al.
Publicado: (2019)

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells
por: Ciaffaglione, Valeria, et al.
Publicado: (2020)

Xth EPR Workshop on Applications of EPR in Biology and Medicine
por: Sarna, Tadeusz, et al.
Publicado: (2017)

Demonstration of interferometer enhancement through EPR entanglement
por: Südbeck, Jan, et al.
Publicado: (2020)

Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia
por: Ciaffaglione, Valeria, et al.
Publicado: (2022)

EPR Everywhere
por: Biller, Joshua R., et al.
Publicado: (2021)

Utilization and Cost of Sildenafil in a Large Managed Care Organization With a Quantity Limit on Sildenafil
por: Cooke, Catherine E., et al.
Publicado: (2005)

A Systematic Review of Sildenafil Mortality Through the Years
por: Al Ibrahim, Abdullah H, et al.
Publicado: (2022)

Why sildenafil and sildenafil citrate monohydrate crystals are not stable?
por: Sawatdee, Somchai, et al.
Publicado: (2015)

Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity
por: Fallica, Antonino N., et al.
Publicado: (2021)

Resurrection of sildenafil: potential for Huntington’s Disease, too?
por: Achenbach, Jannis, et al.
Publicado: (2022)

Soy polysaccharide as a novel superdisintegrant in sildenafil citrate sublingual tablets: preparation, characterization, and in vivo evaluation
por: Hosny, Khaled Mohamed, et al.
Publicado: (2015)

EPR paradox revisited
por: Klippert, R
Publicado: (1999)

Sildenafil potentiates the antitumor activity of cisplatin by induction of apoptosis and inhibition of proliferation and angiogenesis
por: El-Naa, Mona Mohamed, et al.
Publicado: (2016)

Sildenafil augments fetal weight and placental adiponectin in gestational testosterone-induced glucose intolerant rats
por: Areola, Emmanuel Damilare, et al.
Publicado: (2021)

Alliance with EPR Effect: Combined Strategies to Improve the EPR Effect in the Tumor Microenvironment
por: Park, Jooho, et al.
Publicado: (2019)

Sildenafil citrate for the management of fetal growth restriction and oligohydramnios
por: Choudhary, Rana, et al.
Publicado: (2016)

Sildenafil Citrate: Novel Therapy in the Management of Ovarian Torsion
por: Ganla, Kedar N., et al.
Publicado: (2019)

Changes in the Pharmacokinetics and Pharmacodynamics of Sildenafil in Cigarette and Cannabis Smokers
por: Murtadha, Mohammed, et al.
Publicado: (2021)

SILDENAFIL (VIAGRA) AND THE HEART
por: Chamsi-Pasha, Hassan
Publicado: (2001)

Sildenafil in Infants and Children
por: Simonca, Larisa, et al.
Publicado: (2017)

Sildenafil and suicide in Sweden
por: Catalano, Ralph, et al.
Publicado: (2021)

Novel NMR and EPR techniques
por: Dolinšek, Janez, et al.
Publicado: (2006)

EPR in B physics and elsewhere
por: Lipkin, Harry Jeannot
Publicado: (1997)

EPR correlations and EPW distributions
por: Bell, John Stewart
Publicado: (1986)

Computational and instrumental methods in EPR
por: Bender, Christopher J, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_cgrhjttj6hebf4i90ipsnc6vrn