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Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2
Pets play a crucial role in the development of human feelings, social life, and care. However, in the era of the prevailing global pandemic of COVID-19 disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many questions addressing the routes of the virus spread and tra...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234912/ https://www.ncbi.nlm.nih.gov/pubmed/34208484 http://dx.doi.org/10.3390/v13061149 |
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author | Dróżdż, Mateusz Krzyżek, Paweł Dudek, Barbara Makuch, Sebastian Janczura, Adriana Paluch, Emil |
author_facet | Dróżdż, Mateusz Krzyżek, Paweł Dudek, Barbara Makuch, Sebastian Janczura, Adriana Paluch, Emil |
author_sort | Dróżdż, Mateusz |
collection | PubMed |
description | Pets play a crucial role in the development of human feelings, social life, and care. However, in the era of the prevailing global pandemic of COVID-19 disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many questions addressing the routes of the virus spread and transmission to humans are dramatically emerging. Although cases of SARS-CoV-2 infection have been found in pets including dogs, cats, and ferrets, to date there is no strong evidence for pet-to-human transmission or sustained pet-to-pet transmission of SARS-CoV-2. However, an increasing number of studies reporting detection of SARS-CoV-2 in farmed minks raises suspicion of potential viral transmission from these animals to humans. Furthermore, due to the high susceptibility of cats, ferrets, minks and hamsters to COVID-19 infection under natural and/or experimental conditions, these animals have been extensively explored as animal models to study the SARS-CoV-2 pathogenesis and transmission. In this review, we present the latest reports focusing on SARS-CoV-2 detection, isolation, and characterization in pets. Moreover, based on the current literature, we document studies aiming to broaden the knowledge about pathogenicity and transmissibility of SARS-CoV-2, and the development of viral therapeutics, drugs and vaccines. Lastly, considering the high rate of SARS-CoV-2 evolution and replication, we also suggest routes of protection against the virus. |
format | Online Article Text |
id | pubmed-8234912 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82349122021-06-27 Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 Dróżdż, Mateusz Krzyżek, Paweł Dudek, Barbara Makuch, Sebastian Janczura, Adriana Paluch, Emil Viruses Review Pets play a crucial role in the development of human feelings, social life, and care. However, in the era of the prevailing global pandemic of COVID-19 disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many questions addressing the routes of the virus spread and transmission to humans are dramatically emerging. Although cases of SARS-CoV-2 infection have been found in pets including dogs, cats, and ferrets, to date there is no strong evidence for pet-to-human transmission or sustained pet-to-pet transmission of SARS-CoV-2. However, an increasing number of studies reporting detection of SARS-CoV-2 in farmed minks raises suspicion of potential viral transmission from these animals to humans. Furthermore, due to the high susceptibility of cats, ferrets, minks and hamsters to COVID-19 infection under natural and/or experimental conditions, these animals have been extensively explored as animal models to study the SARS-CoV-2 pathogenesis and transmission. In this review, we present the latest reports focusing on SARS-CoV-2 detection, isolation, and characterization in pets. Moreover, based on the current literature, we document studies aiming to broaden the knowledge about pathogenicity and transmissibility of SARS-CoV-2, and the development of viral therapeutics, drugs and vaccines. Lastly, considering the high rate of SARS-CoV-2 evolution and replication, we also suggest routes of protection against the virus. MDPI 2021-06-16 /pmc/articles/PMC8234912/ /pubmed/34208484 http://dx.doi.org/10.3390/v13061149 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Dróżdż, Mateusz Krzyżek, Paweł Dudek, Barbara Makuch, Sebastian Janczura, Adriana Paluch, Emil Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
title | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
title_full | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
title_fullStr | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
title_full_unstemmed | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
title_short | Current State of Knowledge about Role of Pets in Zoonotic Transmission of SARS-CoV-2 |
title_sort | current state of knowledge about role of pets in zoonotic transmission of sars-cov-2 |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234912/ https://www.ncbi.nlm.nih.gov/pubmed/34208484 http://dx.doi.org/10.3390/v13061149 |
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