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Regulatory SNPs: Altered Transcription Factor Binding Sites Implicated in Complex Traits and Diseases
The vast majority of the genetic variants (mainly SNPs) associated with various human traits and diseases map to a noncoding part of the genome and are enriched in its regulatory compartment, suggesting that many causal variants may affect gene expression. The leading mechanism of action of these SN...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235176/ https://www.ncbi.nlm.nih.gov/pubmed/34208629 http://dx.doi.org/10.3390/ijms22126454 |