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Regulatory SNPs: Altered Transcription Factor Binding Sites Implicated in Complex Traits and Diseases

The vast majority of the genetic variants (mainly SNPs) associated with various human traits and diseases map to a noncoding part of the genome and are enriched in its regulatory compartment, suggesting that many causal variants may affect gene expression. The leading mechanism of action of these SN...

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Detalles Bibliográficos
Autores principales:	Degtyareva, Arina O., Antontseva, Elena V., Merkulova, Tatiana I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235176/ https://www.ncbi.nlm.nih.gov/pubmed/34208629 http://dx.doi.org/10.3390/ijms22126454

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