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Study of the Biologically Active Properties of Medicinal Plant Cotinus coggygria

The results of the studies have shown that to obtain an extract of a complex of biologically active substances of Cotinus coggygria, ethyl alcohol (mass fraction of alcohol 70%) with a hydromodule of 1:5 should be used, and the extraction should be carried out for 60 min at a temperature of 60 °C. T...

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Autores principales: Sukhikh, Stanislav, Noskova, Svetlana, Pungin, Artem, Ivanova, Svetlana, Skrypnik, Liubov, Chupakhin, Evgeny, Babich, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235186/
https://www.ncbi.nlm.nih.gov/pubmed/34208532
http://dx.doi.org/10.3390/plants10061224
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author Sukhikh, Stanislav
Noskova, Svetlana
Pungin, Artem
Ivanova, Svetlana
Skrypnik, Liubov
Chupakhin, Evgeny
Babich, Olga
author_facet Sukhikh, Stanislav
Noskova, Svetlana
Pungin, Artem
Ivanova, Svetlana
Skrypnik, Liubov
Chupakhin, Evgeny
Babich, Olga
author_sort Sukhikh, Stanislav
collection PubMed
description The results of the studies have shown that to obtain an extract of a complex of biologically active substances of Cotinus coggygria, ethyl alcohol (mass fraction of alcohol 70%) with a hydromodule of 1:5 should be used, and the extraction should be carried out for 60 min at a temperature of 60 °C. The investigated plant extracts with the complex of bioactive substances from the Cotinus coggygria leaves and flowers are safe from the point of view of the content of heavy metals, pesticides, aflatoxin B1, radionuclides, as well as pathogenic and opportunistic microorganisms. It has been established that the Cotinus coggygria extract contains rutin, hyperoside, ferulic acid, quercetin, kaempferol, disulphuretin, sulphurein, sulphurein, gallic acid, methyl gallate, pentagalloyl glucose, 3,3′,4′,5,6,7-hexahydroxyflavonone, 3,3′,4′,5,5′,7-hexahydroxyflavonone, 3-O-α-L-rhamnofuranoside, 3,3′,4′,5,5′,7-hexahydroxyflavulium(1+), 7-O-β-D glucopyranoside, and 3,3′,4′,7-tetrahydroxyflavonone. The tested extracts have anticancer, antigenotoxic, and antimicrobial (against E. coli, S. aureus, P. vulgaris, C. albicans, L. mesenteroides) properties. The high antioxidant status of the tested extracts was established; the antioxidant activity of the samples was 145.09 mg AA/g (AA—ascorbic acid).
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spelling pubmed-82351862021-06-27 Study of the Biologically Active Properties of Medicinal Plant Cotinus coggygria Sukhikh, Stanislav Noskova, Svetlana Pungin, Artem Ivanova, Svetlana Skrypnik, Liubov Chupakhin, Evgeny Babich, Olga Plants (Basel) Article The results of the studies have shown that to obtain an extract of a complex of biologically active substances of Cotinus coggygria, ethyl alcohol (mass fraction of alcohol 70%) with a hydromodule of 1:5 should be used, and the extraction should be carried out for 60 min at a temperature of 60 °C. The investigated plant extracts with the complex of bioactive substances from the Cotinus coggygria leaves and flowers are safe from the point of view of the content of heavy metals, pesticides, aflatoxin B1, radionuclides, as well as pathogenic and opportunistic microorganisms. It has been established that the Cotinus coggygria extract contains rutin, hyperoside, ferulic acid, quercetin, kaempferol, disulphuretin, sulphurein, sulphurein, gallic acid, methyl gallate, pentagalloyl glucose, 3,3′,4′,5,6,7-hexahydroxyflavonone, 3,3′,4′,5,5′,7-hexahydroxyflavonone, 3-O-α-L-rhamnofuranoside, 3,3′,4′,5,5′,7-hexahydroxyflavulium(1+), 7-O-β-D glucopyranoside, and 3,3′,4′,7-tetrahydroxyflavonone. The tested extracts have anticancer, antigenotoxic, and antimicrobial (against E. coli, S. aureus, P. vulgaris, C. albicans, L. mesenteroides) properties. The high antioxidant status of the tested extracts was established; the antioxidant activity of the samples was 145.09 mg AA/g (AA—ascorbic acid). MDPI 2021-06-16 /pmc/articles/PMC8235186/ /pubmed/34208532 http://dx.doi.org/10.3390/plants10061224 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sukhikh, Stanislav
Noskova, Svetlana
Pungin, Artem
Ivanova, Svetlana
Skrypnik, Liubov
Chupakhin, Evgeny
Babich, Olga
Study of the Biologically Active Properties of Medicinal Plant Cotinus coggygria
title Study of the Biologically Active Properties of Medicinal Plant Cotinus coggygria
title_full Study of the Biologically Active Properties of Medicinal Plant Cotinus coggygria
title_fullStr Study of the Biologically Active Properties of Medicinal Plant Cotinus coggygria
title_full_unstemmed Study of the Biologically Active Properties of Medicinal Plant Cotinus coggygria
title_short Study of the Biologically Active Properties of Medicinal Plant Cotinus coggygria
title_sort study of the biologically active properties of medicinal plant cotinus coggygria
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235186/
https://www.ncbi.nlm.nih.gov/pubmed/34208532
http://dx.doi.org/10.3390/plants10061224
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