Cargando…

One-Carbon Metabolism Associated Vulnerabilities in Glioblastoma: A Review

SIMPLE SUMMARY: Glioblastoma tumours are the most malignant and common type of central nervous system tumours. Despite aggressive treatment measures, disease recurrence in patients with glioblastoma is inevitable and survival rates remain low. Glioblastoma cells, like other cancer cells, can leverag...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghannad-Zadeh, Kimia, Das, Sunit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235277/ https://www.ncbi.nlm.nih.gov/pubmed/34205450 http://dx.doi.org/10.3390/cancers13123067

Ejemplares similares

FSMP-01. ID1 MEDIATES ONE-CARBON MEDIATED PURINE SYNTHESIS IN GLIOBLASTOMA
por: Ghannad-Zadeh, Kimia, et al.
Publicado: (2021)

Targeting serine-glycine-one-carbon metabolism as a vulnerability in cancers
por: Sun, Wei, et al.
Publicado: (2023)

Serine–glycine-one-carbon metabolism: vulnerabilities in MYCN-amplified neuroblastoma
por: Zhao, Erhu, et al.
Publicado: (2020)

IDH3α regulates one-carbon metabolism in glioblastoma
por: May, Jasmine L., et al.
Publicado: (2019)

Noncoding RNAs in Glioblastoma: Emerging Biological Concepts and Potential Therapeutic Implications
por: Shahzad, Uswa, et al.
Publicado: (2021)

Pharmacological targeting of one‑carbon metabolism as a novel therapeutic strategy for glioblastoma
por: Sun, Yanfei, et al.
Publicado: (2023)

Tryptophan Metabolism and Gut-Brain Homeostasis
por: Roth, William, et al.
Publicado: (2021)

Progression-Free but No Overall Survival Benefit for Adult Patients with Bevacizumab Therapy for the Treatment of Newly Diagnosed Glioblastoma: A Systematic Review and Meta-Analysis
por: Kaka, Nagham, et al.
Publicado: (2019)

COVID-19 and One-Carbon Metabolism
por: Perła-Kaján, Joanna, et al.
Publicado: (2022)

Nutrition, One-Carbon Metabolism and Neural Tube Defects: A Review
por: Li, Kelei, et al.
Publicado: (2016)

Metabolic Reprogramming by c-MET Inhibition as a Targetable Vulnerability in Glioblastoma
por: Thi Thu Nguyen, Trang, et al.
Publicado: (2020)

The Antioxidant Role of One-Carbon Metabolism on Stroke
por: Burgess, Kassidy, et al.
Publicado: (2020)

Interactions between Radiation and One-Carbon Metabolism
por: Korimerla, Navyateja, et al.
Publicado: (2022)

Polyamine Metabolism and Gene Methylation in Conjunction with One-Carbon Metabolism
por: Soda, Kuniyasu
Publicado: (2018)

Management of Elderly Patients with Glioblastoma after CE.6
por: Das, Sunit, et al.
Publicado: (2017)

Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells
por: He, Long, et al.
Publicado: (2022)

CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer
por: Filippone, M. G., et al.
Publicado: (2022)

Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells
por: Immanuel, Selva Rupa Christinal, et al.
Publicado: (2021)

The toxic side of one-carbon metabolism and epigenetics
por: Morellato, Agustín E., et al.
Publicado: (2020)

One-Carbon and Polyamine Metabolism as Cancer Therapy Targets
por: Islam, Anowarul, et al.
Publicado: (2022)

The Role of One-Carbon Metabolism in Healthy Brain Aging
por: Virdi, Sapna, et al.
Publicado: (2023)

TREATMENT, HEALTHCARE UTILIZATION AND OUTCOMES IN PATIENTS WITH GLIOBLASTOMA IN ONTARIO: A 10-YEAR COHORT STUDY
por: Rzadki, Kathryn, et al.
Publicado: (2023)

A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma
por: Banu, Matei A., et al.
Publicado: (2023)

Lessons learned from contemporary glioblastoma randomized clinical trials through systematic review and network meta-analysis: part 2 recurrent glioblastoma
por: Taslimi, Shervin, et al.
Publicado: (2021)

Metabolic dependencies and vulnerabilities in leukemia
por: Rashkovan, Marissa, et al.
Publicado: (2019)

Metabolic Vulnerabilities in Multiple Myeloma
por: Lim, Julia S. L., et al.
Publicado: (2022)

Folic acid, one-carbon metabolism & childhood cancer
por: Moulik, Nirmalya Roy, et al.
Publicado: (2017)

One-Carbon Metabolism in Prostate Cancer: The Role of Androgen Signaling
por: Corbin, Joshua M., et al.
Publicado: (2016)

One-Carbon Metabolism: Biological Players in Epithelial Ovarian Cancer
por: Rizzo, Andrea, et al.
Publicado: (2018)

One-Carbon Metabolism: Pulling the Strings behind Aging and Neurodegeneration
por: Lionaki, Eirini, et al.
Publicado: (2022)

Targeted Proteomics for Monitoring One-Carbon Metabolism in Liver Diseases
por: Guerrero, Laura, et al.
Publicado: (2022)

Serine, glycine and one-carbon metabolism in cancer (Review)
por: Pan, Sijing, et al.
Publicado: (2020)

One-carbon metabolism in cancer
por: Newman, Alice C, et al.
Publicado: (2017)

Neuro-Vulnerability in Energy Metabolism Regulation: A Comprehensive Narrative Review
por: Clemente-Suárez, Vicente Javier, et al.
Publicado: (2023)

Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma
por: Nguyen, Trang T. T., et al.
Publicado: (2021)

Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation
por: Zois, Christos E., et al.
Publicado: (2022)

A microRNA Link to Glioblastoma Heterogeneity
por: Singh, Sanjay K., et al.
Publicado: (2012)

Metabolic alterations and vulnerabilities in hepatocellular carcinoma
por: Tenen, Daniel G, et al.
Publicado: (2020)

Lipid metabolic vulnerabilities of multiple myeloma
por: Torcasio, Roberta, et al.
Publicado: (2023)

Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users
por: Luciano-Mateo, Fedra, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3s97cbuaqijbt0t9tj09kro4lu