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Distinct Responsiveness of Tumor-Associated Macrophages to Immunotherapy of Tumors with Different Mechanisms of Major Histocompatibility Complex Class I Downregulation

SIMPLE SUMMARY: Tumor-associated macrophages (TAMs) are one of the major cell subpopulations in the tumor microenvironment (TME) where they can either be pro-tumorigenic or contribute to an anti-tumor immunity. The TME and TAM phenotype were analyzed after combined immuno-therapy (IT) in tumor model...

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Detalles Bibliográficos
Autores principales: Piatakova, Adrianna, Polakova, Ingrid, Smahelova, Jana, Johari, Shweta Dilip, Nunvar, Jaroslav, Smahel, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235485/
https://www.ncbi.nlm.nih.gov/pubmed/34205330
http://dx.doi.org/10.3390/cancers13123057

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