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Long non-coding RNA DLEU2 drives EMT and glycolysis in endometrial cancer through HK2 by competitively binding with miR-455 and by modulating the EZH2/miR-181a pathway

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) and aerobic glycolysis are fundamental processes implicated in cancer metastasis. Although increasing evidence demonstrates an association between EMT induction and enhanced aerobic glycolysis in human cancer, the mechanisms linking these two co...

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Detalles Bibliográficos
Autores principales: Dong, Peixin, Xiong, Ying, Konno, Yosuke, Ihira, Kei, Kobayashi, Noriko, Yue, Junming, Watari, Hidemichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235565/
https://www.ncbi.nlm.nih.gov/pubmed/34174908
http://dx.doi.org/10.1186/s13046-021-02018-1