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Cost-effectiveness of specialist eating disorders services for children and adolescents with anorexia nervosa: a national surveillance study
BACKGROUND: Evidence suggests specialist eating disorders services for children and adolescents with anorexia nervosa have the potential to improve outcomes and reduce costs through reduced hospital admissions. This study aimed to evaluate the cost-effectiveness of assessment and diagnosis in commun...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235580/ https://www.ncbi.nlm.nih.gov/pubmed/34174952 http://dx.doi.org/10.1186/s40337-021-00433-5 |
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author | Byford, Sarah Petkova, Hristina Barrett, Barbara Ford, Tamsin Nicholls, Dasha Simic, Mima Gowers, Simon Macdonald, Geraldine Stuart, Ruth Livingstone, Nuala Kelly, Grace Kelly, Jonathan Joshi, Kandarp Smith, Helen Eisler, Ivan |
author_facet | Byford, Sarah Petkova, Hristina Barrett, Barbara Ford, Tamsin Nicholls, Dasha Simic, Mima Gowers, Simon Macdonald, Geraldine Stuart, Ruth Livingstone, Nuala Kelly, Grace Kelly, Jonathan Joshi, Kandarp Smith, Helen Eisler, Ivan |
author_sort | Byford, Sarah |
collection | PubMed |
description | BACKGROUND: Evidence suggests specialist eating disorders services for children and adolescents with anorexia nervosa have the potential to improve outcomes and reduce costs through reduced hospital admissions. This study aimed to evaluate the cost-effectiveness of assessment and diagnosis in community-based specialist child and adolescent mental health services (CAMHS) compared to generic CAMHS for children and adolescents with anorexia nervosa. METHOD: Observational, surveillance study of children and adolescents aged 8 to 17, in contact with community-based CAMHS in the UK or Republic of Ireland for a first episode of anorexia nervosa. Data were reported by clinicians at baseline, 6 and 12-months follow-up. Outcomes included the Children’s Global Assessment Scale (CGAS) and percentage of median expected body mass for age and sex (%mBMI). Service use data included paediatric and psychiatric inpatient admissions, outpatient and day-patient attendances. A joint distribution of incremental mean costs and effects for each group was generated using bootstrapping to explore the probability that each service is the optimal choice, subject to a range of values a decision-maker might be willing to pay for outcome improvements. Uncertainty was explored using cost-effectiveness acceptability curves. RESULTS: Two hundred ninety-eight children and adolescents met inclusion criteria. At 12-month follow-up, there were no significant differences in total costs or outcomes between specialist eating disorders services and generic CAMHS. However, adjustment for pre-specified baseline covariates resulted in observed differences favouring specialist services, due to significantly poorer clinical status of the specialist group at baseline. Cost-effectiveness analysis using CGAS suggests that the probability of assessment in a specialist service being cost-effective compared to generic CAMHS ranges from 90 to 50%, dependent on willingness to pay for improvements in outcome. CONCLUSIONS: Assessment in a specialist eating disorders service for children and adolescents with anorexia nervosa may have a higher probability of being cost-effective than assessment in generic CAMHS. TRIAL REGISTRATION: ISRCTN12676087. Date of registration 07/01/2014. |
format | Online Article Text |
id | pubmed-8235580 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-82355802021-06-28 Cost-effectiveness of specialist eating disorders services for children and adolescents with anorexia nervosa: a national surveillance study Byford, Sarah Petkova, Hristina Barrett, Barbara Ford, Tamsin Nicholls, Dasha Simic, Mima Gowers, Simon Macdonald, Geraldine Stuart, Ruth Livingstone, Nuala Kelly, Grace Kelly, Jonathan Joshi, Kandarp Smith, Helen Eisler, Ivan J Eat Disord Research Article BACKGROUND: Evidence suggests specialist eating disorders services for children and adolescents with anorexia nervosa have the potential to improve outcomes and reduce costs through reduced hospital admissions. This study aimed to evaluate the cost-effectiveness of assessment and diagnosis in community-based specialist child and adolescent mental health services (CAMHS) compared to generic CAMHS for children and adolescents with anorexia nervosa. METHOD: Observational, surveillance study of children and adolescents aged 8 to 17, in contact with community-based CAMHS in the UK or Republic of Ireland for a first episode of anorexia nervosa. Data were reported by clinicians at baseline, 6 and 12-months follow-up. Outcomes included the Children’s Global Assessment Scale (CGAS) and percentage of median expected body mass for age and sex (%mBMI). Service use data included paediatric and psychiatric inpatient admissions, outpatient and day-patient attendances. A joint distribution of incremental mean costs and effects for each group was generated using bootstrapping to explore the probability that each service is the optimal choice, subject to a range of values a decision-maker might be willing to pay for outcome improvements. Uncertainty was explored using cost-effectiveness acceptability curves. RESULTS: Two hundred ninety-eight children and adolescents met inclusion criteria. At 12-month follow-up, there were no significant differences in total costs or outcomes between specialist eating disorders services and generic CAMHS. However, adjustment for pre-specified baseline covariates resulted in observed differences favouring specialist services, due to significantly poorer clinical status of the specialist group at baseline. Cost-effectiveness analysis using CGAS suggests that the probability of assessment in a specialist service being cost-effective compared to generic CAMHS ranges from 90 to 50%, dependent on willingness to pay for improvements in outcome. CONCLUSIONS: Assessment in a specialist eating disorders service for children and adolescents with anorexia nervosa may have a higher probability of being cost-effective than assessment in generic CAMHS. TRIAL REGISTRATION: ISRCTN12676087. Date of registration 07/01/2014. BioMed Central 2021-06-26 /pmc/articles/PMC8235580/ /pubmed/34174952 http://dx.doi.org/10.1186/s40337-021-00433-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Byford, Sarah Petkova, Hristina Barrett, Barbara Ford, Tamsin Nicholls, Dasha Simic, Mima Gowers, Simon Macdonald, Geraldine Stuart, Ruth Livingstone, Nuala Kelly, Grace Kelly, Jonathan Joshi, Kandarp Smith, Helen Eisler, Ivan Cost-effectiveness of specialist eating disorders services for children and adolescents with anorexia nervosa: a national surveillance study |
title | Cost-effectiveness of specialist eating disorders services for children and adolescents with anorexia nervosa: a national surveillance study |
title_full | Cost-effectiveness of specialist eating disorders services for children and adolescents with anorexia nervosa: a national surveillance study |
title_fullStr | Cost-effectiveness of specialist eating disorders services for children and adolescents with anorexia nervosa: a national surveillance study |
title_full_unstemmed | Cost-effectiveness of specialist eating disorders services for children and adolescents with anorexia nervosa: a national surveillance study |
title_short | Cost-effectiveness of specialist eating disorders services for children and adolescents with anorexia nervosa: a national surveillance study |
title_sort | cost-effectiveness of specialist eating disorders services for children and adolescents with anorexia nervosa: a national surveillance study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235580/ https://www.ncbi.nlm.nih.gov/pubmed/34174952 http://dx.doi.org/10.1186/s40337-021-00433-5 |
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