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Targeting the Ubiquitin-Proteasome System for Cancer Therapeutics by Small-Molecule Inhibitors

SIMPLE SUMMARY: The ubiquitin-proteasome system regulates multiple facets of protein homeostasis to modulate signal transduction in numerous biological processes. Not surprisingly, dysregulation of this delicately balanced system is frequently observed in cancer progression. In the past two decades,...

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Detalles Bibliográficos
Autores principales:	LaPlante, Gabriel, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235664/ https://www.ncbi.nlm.nih.gov/pubmed/34203106 http://dx.doi.org/10.3390/cancers13123079

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