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Iris Melanocytoma in a Child: Clinical and Histopathological Findings

Patient: Male, 3-year-old Final Diagnosis: Iris melanocytoma Symptoms: Eye pain and redness • photophobia Medication: — Clinical Procedure: — Specialty: Ophthalmology OBJECTIVE: Rare disease BACKGROUND: Melanocytoma is rare and can affect any part of the uveal tract. In rare cases, iris melanocytoma...

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Autores principales: Al-Kharashi, Abdulkarim, Alsakran, Wael A., Alshamrani, Abdulaziz A., AlZaid, Abdulrahman, Maktabi, Azza M.Y., Alzahrani, Yahya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235677/
https://www.ncbi.nlm.nih.gov/pubmed/34153023
http://dx.doi.org/10.12659/AJCR.931385
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author Al-Kharashi, Abdulkarim
Alsakran, Wael A.
Alshamrani, Abdulaziz A.
AlZaid, Abdulrahman
Maktabi, Azza M.Y.
Alzahrani, Yahya A.
author_facet Al-Kharashi, Abdulkarim
Alsakran, Wael A.
Alshamrani, Abdulaziz A.
AlZaid, Abdulrahman
Maktabi, Azza M.Y.
Alzahrani, Yahya A.
author_sort Al-Kharashi, Abdulkarim
collection PubMed
description Patient: Male, 3-year-old Final Diagnosis: Iris melanocytoma Symptoms: Eye pain and redness • photophobia Medication: — Clinical Procedure: — Specialty: Ophthalmology OBJECTIVE: Rare disease BACKGROUND: Melanocytoma is rare and can affect any part of the uveal tract. In rare cases, iris melanocytoma shows signs of growth, with extrascleral extension that mimics melanoma. This phenomenon makes clinical differentiation between the 2 pathologies particularly challenging. CASE REPORT: A 3-year-old boy presented with recurrent ocular inflammation. Examination revealed a large, solid, homogenous mass in the inferior quadrants of the iris, with secondary localized corneal edema. The lesion did not extend to the ciliary body and fundus examination showed no lesions in the posterior segment, including the head of the optic nerve. The patient underwent a sectoral iridocyclectomy and excisional biopsy of the lesion in the iris. Histopathology of the lesion confirmed the diagnosis of iris melanocytoma. CONCLUSIONS: The differential diagnosis for a mass in the iris is broad, ranging from benign cysts to melanoma, which is a life-threatening ocular condition. An iris melanocytoma always should be considered in the differential of these masses, despite their exceedingly low incidence. Although iris melanocytoma mainly manifests in patients who are middle-aged or older, it should be suspected in young children, as underscored by the present report.
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spelling pubmed-82356772021-07-02 Iris Melanocytoma in a Child: Clinical and Histopathological Findings Al-Kharashi, Abdulkarim Alsakran, Wael A. Alshamrani, Abdulaziz A. AlZaid, Abdulrahman Maktabi, Azza M.Y. Alzahrani, Yahya A. Am J Case Rep Articles Patient: Male, 3-year-old Final Diagnosis: Iris melanocytoma Symptoms: Eye pain and redness • photophobia Medication: — Clinical Procedure: — Specialty: Ophthalmology OBJECTIVE: Rare disease BACKGROUND: Melanocytoma is rare and can affect any part of the uveal tract. In rare cases, iris melanocytoma shows signs of growth, with extrascleral extension that mimics melanoma. This phenomenon makes clinical differentiation between the 2 pathologies particularly challenging. CASE REPORT: A 3-year-old boy presented with recurrent ocular inflammation. Examination revealed a large, solid, homogenous mass in the inferior quadrants of the iris, with secondary localized corneal edema. The lesion did not extend to the ciliary body and fundus examination showed no lesions in the posterior segment, including the head of the optic nerve. The patient underwent a sectoral iridocyclectomy and excisional biopsy of the lesion in the iris. Histopathology of the lesion confirmed the diagnosis of iris melanocytoma. CONCLUSIONS: The differential diagnosis for a mass in the iris is broad, ranging from benign cysts to melanoma, which is a life-threatening ocular condition. An iris melanocytoma always should be considered in the differential of these masses, despite their exceedingly low incidence. Although iris melanocytoma mainly manifests in patients who are middle-aged or older, it should be suspected in young children, as underscored by the present report. International Scientific Literature, Inc. 2021-06-21 /pmc/articles/PMC8235677/ /pubmed/34153023 http://dx.doi.org/10.12659/AJCR.931385 Text en © Am J Case Rep, 2021 https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Al-Kharashi, Abdulkarim
Alsakran, Wael A.
Alshamrani, Abdulaziz A.
AlZaid, Abdulrahman
Maktabi, Azza M.Y.
Alzahrani, Yahya A.
Iris Melanocytoma in a Child: Clinical and Histopathological Findings
title Iris Melanocytoma in a Child: Clinical and Histopathological Findings
title_full Iris Melanocytoma in a Child: Clinical and Histopathological Findings
title_fullStr Iris Melanocytoma in a Child: Clinical and Histopathological Findings
title_full_unstemmed Iris Melanocytoma in a Child: Clinical and Histopathological Findings
title_short Iris Melanocytoma in a Child: Clinical and Histopathological Findings
title_sort iris melanocytoma in a child: clinical and histopathological findings
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235677/
https://www.ncbi.nlm.nih.gov/pubmed/34153023
http://dx.doi.org/10.12659/AJCR.931385
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