Formulation of Chewable Tablets Containing Carbamazepine-β-cyclodextrin Inclusion Complex and F-Melt Disintegration Excipient. The Mathematical Modeling of the Release Kinetics of Carbamazepine

Due to its low solubility, carbamazepine (CBZ) exhibits slow and incomplete release in the gastrointestinal tract and, hence, variable pharmacokinetics and pharmacodynamic effect. Lots of methods have been devised to improve its solubility, the large number of proposed solutions being a sign that th...

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Detalles Bibliográficos
Autores principales: Musuc, Adina Magdalena, Anuta, Valentina, Atkinson, Irina, Sarbu, Iulian, Popa, Vlad Tudor, Munteanu, Cornel, Mircioiu, Constantin, Ozon, Emma Adriana, Nitulescu, George Mihai, Mitu, Mirela Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235681/
https://www.ncbi.nlm.nih.gov/pubmed/34205629
http://dx.doi.org/10.3390/pharmaceutics13060915

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