New RAD51 Inhibitors to Target Homologous Recombination in Human Cells

Targeting DNA repair proteins with small-molecule inhibitors became a proven anti-cancer strategy. Previously, we identified an inhibitor of a major protein of homologous recombination (HR) RAD51, named B02. B02 inhibited HR in human cells and sensitized them to chemotherapeutic drugs in vitro and i...

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Detalles Bibliográficos
Autores principales: Shkundina, Irina S., Gall, Alexander A., Dick, Alexej, Cocklin, Simon, Mazin, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235719/
https://www.ncbi.nlm.nih.gov/pubmed/34208492
http://dx.doi.org/10.3390/genes12060920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235719/
https://www.ncbi.nlm.nih.gov/pubmed/34208492
http://dx.doi.org/10.3390/genes12060920

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