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Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia

Reductions in the GABAergic neurotransmitter system exist across multiple brain regions in schizophrenia and encompass both pre- and postsynaptic components. While reduced midbrain GABAergic inhibitory neurotransmission may contribute to the hyperdopaminergia thought to underpin psychosis in schizop...

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Detalles Bibliográficos
Autores principales: Purves-Tyson, Tertia D., Brown, Amelia M., Weissleder, Christin, Rothmond, Debora A., Shannon Weickert, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235806/
https://www.ncbi.nlm.nih.gov/pubmed/34174930
http://dx.doi.org/10.1186/s13041-021-00805-7