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Distinct BTK inhibitors differentially induce apoptosis but similarly suppress chemotaxis and lipid accumulation in mantle cell lymphoma

BACKGROUND: The more selective second-generation BTK inhibitors (BTKi) Acalabrutinib and Zanubrutinib and the first-generation BTKi Ibrutinib are highlighted by their clinical effectiveness in mantle cell lymphoma (MCL), however, similarities and differences of their biological and molecular effects...

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Detalles Bibliográficos
Autores principales: Liu, Zhuojun, Liu, Jia, Zhang, Tianming, Li, Lin, Zhang, Shuo, Jia, Hao, Xia, Yuanshi, Shi, Mingxia, Zhang, Jing, Yue, Shuhua, Chen, Xiaofang, Yu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235860/
https://www.ncbi.nlm.nih.gov/pubmed/34174847
http://dx.doi.org/10.1186/s12885-021-08475-3