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Ovarian cycle stage critically affects 21-gene recurrence scores in Mmtv-Pymt mouse mammary tumours
BACKGROUND: The Oncotype DX 21-gene Recurrence Score is predictive of adjuvant chemotherapy benefit for women with early-stage, estrogen receptor (ER)-positive, HER2-negative breast cancer. In premenopausal women, fluctuations in estrogen and progesterone during the menstrual cycle impact gene expre...
Autores principales: | Bernhardt, Sarah M., Dasari, Pallave, Glynn, Danielle J., Woolford, Lucy, Moldenhauer, Lachlan M., Walsh, David, Townsend, Amanda R., Price, Timothy J., Ingman, Wendy V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236154/ https://www.ncbi.nlm.nih.gov/pubmed/34174867 http://dx.doi.org/10.1186/s12885-021-08496-y |
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