Activation of the Anti-Oxidative Stress Response Reactivates Latent HIV-1 Through the Mitochondrial Antiviral Signaling Protein Isoform MiniMAVS

The mitochondrial antiviral signaling protein (MAVS) is part of the cell’s innate immune mechanism of defense. MAVS mRNA is bicistronic and can give rise to a full length-MAVS and a shorter isoform termed miniMAVS. In response to viral infections, viral RNA can be sensed by the cytosolic RNA sensors...

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Detalles Bibliográficos
Autores principales: Sarabia, Indra, Novis, Camille L., Macedo, Amanda B., Takata, Hiroshi, Nell, Racheal, Kakazu, Juyeon C., Furler, Robert L., Shakya, Binita, Schubert, Heidi L., Hill, Christopher P., DePaula-Silva, Ana Beatriz, Spivak, Adam M., Trautmann, Lydie, Planelles, Vicente, Bosque, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236643/
https://www.ncbi.nlm.nih.gov/pubmed/34194436
http://dx.doi.org/10.3389/fimmu.2021.682182

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