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WASp Is Crucial for the Unique Architecture of the Immunological Synapse in Germinal Center B-Cells
B-cells undergo somatic hypermutation and affinity maturation in germinal centers. Somatic hypermutated germinal center B-cells (GCBs) compete to engage with and capture antigens on follicular dendritic cells. Recent studies show that when encountering membrane antigens, GCBs generate actin-rich pod...
Autores principales: | Li, Yanan, Bhanja, Anshuman, Upadhyaya, Arpita, Zhao, Xiaodong, Song, Wenxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236648/ https://www.ncbi.nlm.nih.gov/pubmed/34195186 http://dx.doi.org/10.3389/fcell.2021.646077 |
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