Cargando…
Characterization of CD8 T Cell-Mediated Mutations in the Immunodominant Epitope GP33-41 of Lymphocytic Choriomeningitis Virus
Cytotoxic T lymphocytes (CTLs) represent key immune effectors of the host response against chronic viruses, due to their cytotoxic response to virus-infected cells. In response to this selection pressure, viruses may accumulate escape mutations that evade CTL-mediated control. To study the emergence...
Autores principales: | Smyth, Mark, Khamina, Kseniya, Popa, Alexandra, Gudipati, Venugopal, Agerer, Benedikt, Lercher, Alexander, Kosack, Lindsay, Endler, Lukas, Baazim, Hatoon, Viczenczova, Csilla, Huppa, Johannes B., Bergthaler, Andreas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236698/ https://www.ncbi.nlm.nih.gov/pubmed/34194424 http://dx.doi.org/10.3389/fimmu.2021.638485 |
Ejemplares similares
-
Systemic Immunometabolism: Challenges and Opportunities
por: Lercher, Alexander, et al.
Publicado: (2020) -
Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis
por: Lercher, Alexander, et al.
Publicado: (2020) -
Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein
por: Khamina, Kseniya, et al.
Publicado: (2017) -
CD8(+) T cells induce cachexia during chronic viral infection
por: Baazim, Hatoon, et al.
Publicado: (2019) -
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease
por: Kosack, Lindsay, et al.
Publicado: (2019)