Alteration of Cholesterol Metabolism by Metformin Is Associated With Improved Outcome in Type II Diabetic Patients With Diffuse Large B-Cell Lymphoma

Recent studies have demonstrated the benefits of metformin on patients with lymphomas. B-cell receptor (BCR)-PI3K-AKT pathway-dependent cholesterol synthesis may represent a positive feedback mechanism responsible for the pathogenesis of BCR-dependent diffuse large B-cell lymphomas (DLBCLs). Thus, r...

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Detalles Bibliográficos
Autores principales: Jiang, Xiang-Nan, Zhang, Yan, Wang, Wei-Ge, Sheng, Dong, Zhou, Xiao-Yan, Li, Xiao-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236717/
https://www.ncbi.nlm.nih.gov/pubmed/34195068
http://dx.doi.org/10.3389/fonc.2021.608238

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