Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products

The COPD susceptibility SNP rs2070600 affects the levels of the COPD biomarker sRAGE in sputum as well as splicing of AGER. Moreover, @PouwelsScience et al. demonstrate large differences in sRAGE levels between serum and sputum. https://bit.ly/3t0pJtK

Detalles Bibliográficos
Autores principales: Faiz, Alen, Rathnayake, Senani N.H., ten Hacken, Nick H.T., Guryev, Victor, van den Berge, Maarten, Pouwels, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236754/
https://www.ncbi.nlm.nih.gov/pubmed/34195255
http://dx.doi.org/10.1183/23120541.00947-2020
Descripción
Sumario:The COPD susceptibility SNP rs2070600 affects the levels of the COPD biomarker sRAGE in sputum as well as splicing of AGER. Moreover, @PouwelsScience et al. demonstrate large differences in sRAGE levels between serum and sputum. https://bit.ly/3t0pJtK

Ejemplares similares