Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products

The COPD susceptibility SNP rs2070600 affects the levels of the COPD biomarker sRAGE in sputum as well as splicing of AGER. Moreover, @PouwelsScience et al. demonstrate large differences in sRAGE levels between serum and sputum. https://bit.ly/3t0pJtK

Detalles Bibliográficos
Autores principales: Faiz, Alen, Rathnayake, Senani N.H., ten Hacken, Nick H.T., Guryev, Victor, van den Berge, Maarten, Pouwels, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236754/
https://www.ncbi.nlm.nih.gov/pubmed/34195255
http://dx.doi.org/10.1183/23120541.00947-2020
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author Faiz, Alen
Rathnayake, Senani N.H.
ten Hacken, Nick H.T.
Guryev, Victor
van den Berge, Maarten
Pouwels, Simon D.
author_facet Faiz, Alen
Rathnayake, Senani N.H.
ten Hacken, Nick H.T.
Guryev, Victor
van den Berge, Maarten
Pouwels, Simon D.
author_sort Faiz, Alen
collection PubMed
description The COPD susceptibility SNP rs2070600 affects the levels of the COPD biomarker sRAGE in sputum as well as splicing of AGER. Moreover, @PouwelsScience et al. demonstrate large differences in sRAGE levels between serum and sputum. https://bit.ly/3t0pJtK
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spelling pubmed-82367542021-06-29 Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products Faiz, Alen Rathnayake, Senani N.H. ten Hacken, Nick H.T. Guryev, Victor van den Berge, Maarten Pouwels, Simon D. ERJ Open Res Original Research Letters The COPD susceptibility SNP rs2070600 affects the levels of the COPD biomarker sRAGE in sputum as well as splicing of AGER. Moreover, @PouwelsScience et al. demonstrate large differences in sRAGE levels between serum and sputum. https://bit.ly/3t0pJtK European Respiratory Society 2021-06-28 /pmc/articles/PMC8236754/ /pubmed/34195255 http://dx.doi.org/10.1183/23120541.00947-2020 Text en Copyright ©The authors 2021 https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org)
spellingShingle Original Research Letters
Faiz, Alen
Rathnayake, Senani N.H.
ten Hacken, Nick H.T.
Guryev, Victor
van den Berge, Maarten
Pouwels, Simon D.
Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products
title Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products
title_full Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products
title_fullStr Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products
title_full_unstemmed Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products
title_short Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products
title_sort single-nucleotide polymorphism rs2070600 regulates ager splicing and the sputum levels of the copd biomarker soluble receptor for advanced glycation end-products
topic Original Research Letters
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236754/
https://www.ncbi.nlm.nih.gov/pubmed/34195255
http://dx.doi.org/10.1183/23120541.00947-2020
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