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Clinical Features of COVID-19 Patients With Venous Thromboembolism

This study aimed to assess the clinical features of coronavirus disease 2019 (COVID-19) patients with VTE, to help develop preventive measures for venous thromboembolism (VTE in COVID-19) cases. COVID-19 patients admitted to Henan Provincial People’s Hospital were retrospectively analyzed, including...

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Autores principales: Liang, Kai, Fu, Ying, Kang, Yi, Shao, Huanzhang, Yang, Jianxu, Cui, Mingzhe, Zhai, Shuiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236764/
https://www.ncbi.nlm.nih.gov/pubmed/34169772
http://dx.doi.org/10.1177/10760296211013104
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author Liang, Kai
Fu, Ying
Kang, Yi
Shao, Huanzhang
Yang, Jianxu
Cui, Mingzhe
Zhai, Shuiting
author_facet Liang, Kai
Fu, Ying
Kang, Yi
Shao, Huanzhang
Yang, Jianxu
Cui, Mingzhe
Zhai, Shuiting
author_sort Liang, Kai
collection PubMed
description This study aimed to assess the clinical features of coronavirus disease 2019 (COVID-19) patients with VTE, to help develop preventive measures for venous thromboembolism (VTE in COVID-19) cases. COVID-19 patients admitted to Henan Provincial People’s Hospital were retrospectively analyzed, including 23, 4 and 8 cases with mild to moderate, severe and critical symptoms, respectively. VTE incidence, age at onset, relevant laboratory parameters and prognosis were analyzed. Overall, VTE incidence in the 35 patients was 20.0%, occurring in severe (n = 1) and critical (n = 6) cases. D-dimer showed statistical significance in laboratory examination, representing except a diagnostic index and especial can be a prognostic factor in VTE among COVID-19 patients. Severe and critical COVID-19 cases had significantly reduced platelet counts, with a risk of hemorrhage. During treatment, the risk of both hemorrhage and thrombosis should be considered. VTE occurs in COVID-19 cases, affecting individuals with severe and critical symptoms. Significant D-dimer increase is of great significance in the risk assessment of death in critical cases of COVID-19. Appropriate measures should be taken to prevent VTE during treatment.
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spelling pubmed-82367642021-07-08 Clinical Features of COVID-19 Patients With Venous Thromboembolism Liang, Kai Fu, Ying Kang, Yi Shao, Huanzhang Yang, Jianxu Cui, Mingzhe Zhai, Shuiting Clin Appl Thromb Hemost Original Article This study aimed to assess the clinical features of coronavirus disease 2019 (COVID-19) patients with VTE, to help develop preventive measures for venous thromboembolism (VTE in COVID-19) cases. COVID-19 patients admitted to Henan Provincial People’s Hospital were retrospectively analyzed, including 23, 4 and 8 cases with mild to moderate, severe and critical symptoms, respectively. VTE incidence, age at onset, relevant laboratory parameters and prognosis were analyzed. Overall, VTE incidence in the 35 patients was 20.0%, occurring in severe (n = 1) and critical (n = 6) cases. D-dimer showed statistical significance in laboratory examination, representing except a diagnostic index and especial can be a prognostic factor in VTE among COVID-19 patients. Severe and critical COVID-19 cases had significantly reduced platelet counts, with a risk of hemorrhage. During treatment, the risk of both hemorrhage and thrombosis should be considered. VTE occurs in COVID-19 cases, affecting individuals with severe and critical symptoms. Significant D-dimer increase is of great significance in the risk assessment of death in critical cases of COVID-19. Appropriate measures should be taken to prevent VTE during treatment. SAGE Publications 2021-06-25 /pmc/articles/PMC8236764/ /pubmed/34169772 http://dx.doi.org/10.1177/10760296211013104 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Liang, Kai
Fu, Ying
Kang, Yi
Shao, Huanzhang
Yang, Jianxu
Cui, Mingzhe
Zhai, Shuiting
Clinical Features of COVID-19 Patients With Venous Thromboembolism
title Clinical Features of COVID-19 Patients With Venous Thromboembolism
title_full Clinical Features of COVID-19 Patients With Venous Thromboembolism
title_fullStr Clinical Features of COVID-19 Patients With Venous Thromboembolism
title_full_unstemmed Clinical Features of COVID-19 Patients With Venous Thromboembolism
title_short Clinical Features of COVID-19 Patients With Venous Thromboembolism
title_sort clinical features of covid-19 patients with venous thromboembolism
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236764/
https://www.ncbi.nlm.nih.gov/pubmed/34169772
http://dx.doi.org/10.1177/10760296211013104
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