Biological Role of MYCN in Medulloblastoma: Novel Therapeutic Opportunities and Challenges Ahead

The constitutive and dysregulated expression of the transcription factor MYCN has a central role in the pathogenesis of the paediatric brain tumour medulloblastoma, with an increased expression of this oncogene correlating with a worse prognosis. Consequently, the genomic and functional alterations...

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Detalles Bibliográficos
Autores principales: Shrestha, Sumana, Morcavallo, Alaide, Gorrini, Chiara, Chesler, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236857/
https://www.ncbi.nlm.nih.gov/pubmed/34195095
http://dx.doi.org/10.3389/fonc.2021.694320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236857/
https://www.ncbi.nlm.nih.gov/pubmed/34195095
http://dx.doi.org/10.3389/fonc.2021.694320

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