CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation

The Scar/WAVE complex drives actin nucleation during cell migration. Interestingly, the same complex is important in forming membrane ruffles during macropinocytosis, a process mediating nutrient uptake and membrane receptor trafficking. Mammalian CYRI-B is a recently described negative regulator of...

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Detalles Bibliográficos
Autores principales: Le, Anh Hoang, Yelland, Tamas, Paul, Nikki R., Fort, Loic, Nikolaou, Savvas, Ismail, Shehab, Machesky, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236918/
https://www.ncbi.nlm.nih.gov/pubmed/34165494
http://dx.doi.org/10.1083/jcb.202012114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236918/
https://www.ncbi.nlm.nih.gov/pubmed/34165494
http://dx.doi.org/10.1083/jcb.202012114

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