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CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation
The Scar/WAVE complex drives actin nucleation during cell migration. Interestingly, the same complex is important in forming membrane ruffles during macropinocytosis, a process mediating nutrient uptake and membrane receptor trafficking. Mammalian CYRI-B is a recently described negative regulator of...
Autores principales: | Le, Anh Hoang, Yelland, Tamas, Paul, Nikki R., Fort, Loic, Nikolaou, Savvas, Ismail, Shehab, Machesky, Laura M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236918/ https://www.ncbi.nlm.nih.gov/pubmed/34165494 http://dx.doi.org/10.1083/jcb.202012114 |
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