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HBV Integration Induces Complex Interactions between Host and Viral Genomic Functions at the Insertion Site

Hepatitis B virus (HBV), one of the well-known DNA oncogenic viruses, is the leading cause of hepatocellular carcinoma (HCC). In infected hepatocytes, HBV DNA can be integrated into the host genome through an insertional mutagenesis process inducing tumorigenesis. Dissection of the genomic features...

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Detalles Bibliográficos
Autores principales: Zhang, Dake, Zhang, Ke, Protzer, Urlike, Zeng, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237140/
https://www.ncbi.nlm.nih.gov/pubmed/34221926
http://dx.doi.org/10.14218/JCTH.2021.00062