Cargando…
PD-1 Involvement in Peripheral Blood CD8(+) T Lymphocyte Dysfunction in Patients with Acute-on-chronic Liver Failure
BACKGROUND AND AIMS: Programmed cell death-1 (PD-1) plays an important role in downregulating T lymphocytes but the mechanisms are still poorly understood. This study aimed to explore the role of PD-1 in CD8(+) T lymphocyte dysfunction in hepatitis B virus (HBV)-related acute-on-chronic liver failur...
Autores principales: | Zhou, Xiaoshuang, Li, Yidong, Ji, Yaqiu, Liu, Tian, Zhao, Ninghui, He, Jiefeng, Yao, Jia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
XIA & HE Publishing Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237147/ https://www.ncbi.nlm.nih.gov/pubmed/34221914 http://dx.doi.org/10.14218/JCTH.2020.00142 |
Ejemplares similares
-
Peripheral CD8+CD28+ T lymphocytes predict the efficacy and safety of PD-1/PD-L1 inhibitors in cancer patients
por: Geng, Ruixuan, et al.
Publicado: (2023) -
Genetic landscape and immune mechanism of monocytes associated with the progression of acute-on-chronic liver failure
por: Yao, Jia, et al.
Publicado: (2023) -
PD-1 signaling affects cristae morphology and leads to mitochondrial dysfunction in human CD8(+) T lymphocytes
por: Ogando, Jesús, et al.
Publicado: (2019) -
Decreased peripheral CD4(+)/CD8(+ )lymphocytes and poor prognosis in aged sepsis
por: Inoue, S, et al.
Publicado: (2012) -
Peripheral tolerance induced by apoptotic cells and PD-1+ CD8 T cells
por: Kazama, Hirotaka, et al.
Publicado: (2012)